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Stockholders' Equity - Stock Option Activity (Details) - USD ($)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Shares    
Stock options outstanding at beginning of period 2,954,315 1,480,139
Granted 4,307,599 1,674,153
Exercised (12,765) (70,967)
Expired (82,253) (49,532)
Forfeited (130,022) (79,478)
Stock options outstanding at end of period 7,036,874 2,954,315
Stock options exercisable at end of period 1,680,455  
Weighted Average Exercise Price    
Stock options outstanding at beginning of period (in dollars per share) $ 7.62 $ 11.05
Granted (in dollars per share) 1.10 4.65
Exercised (in dollars per share) 1.30 6.53
Expired (in dollars per share) 10.20 14.26
Forfeited 4.44 5.55
Stock options outstanding at end of period (in dollars per share) 3.67 $ 7.62
Stock options exercisable at end of period $ 9.63  
Aggregate Intrinsic Value    
Stock options outstanding at beginning of period $ 100,419 $ 403,743
Stock options outstanding at end of period 16,842 $ 100,419
Stock options exercisable at end of period $ 16,841  
Weighted Average Remaining Contractual Life    
Stock options outstanding at end of period 9 years 1 month 6 days  
Stock options exercisable at end of period 7 years 6 months  
Unrecognized stock-based compensation expense $ 5,400,000  
Unrecognized stock-based compensation expense, recognition period 1 year 3 months 18 days  
Weighted-average fair value of options $ 0.87 $ 3.67