Goodwill and other intangible assets - Carrying amount of goodwill and intangible assets (Details) - USD ($)	3 Months Ended		12 Months Ended
	Sep. 30, 2022	Dec. 31, 2021	Dec. 31, 2022	Dec. 31, 2021
Goodwill
Goodwill beginning balance				$ 1,452,338
Impairment				(1,452,338)
Acquisition of Elusys Therapeutics			$ 5,067,748
Measurement period adjustments			(1,765,789)
Goodwill ending balance	$ 3,214,747		3,301,959
Intangible Assets
Intangible assets beginning balance			3,500,000
Impairment			(3,500,000)	(2,366,000)
Amortization			(1,030,625)
Intangible assets, ending balance		$ 3,500,000	8,669,375	3,500,000
In-process R&D.
Goodwill
Goodwill beginning balance			1,500,000
Impairment				(1,500,000)
Goodwill ending balance		1,500,000		1,500,000
Intangible Assets
Intangible assets beginning balance			3,500,000	5,866,000
Impairment		(2,400,000)	(3,500,000)	(2,366,000)
Intangible assets, ending balance		3,500,000	3,500,000	3,500,000
Intangible Assets
Intangible Assets
Intangible assets beginning balance
Impairment
Acquisition of Elusys Therapeutics			11,200,000
Measurement period adjustments			(1,500,000)
Amortization			(1,030,625)
Intangible assets, ending balance			$ 8,669,375