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Goodwill and other intangible assets (Details) - USD ($)
3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2022
Dec. 31, 2021
Jun. 30, 2021
Jun. 30, 2022
Dec. 31, 2017
Sep. 30, 2021
Goodwill and other intangible assets            
Balance of finite-lived intangible assets $ 14,350,000 $ 3,500,000   $ 14,350,000    
Estimated useful life       80 months    
In-process R&D.            
Goodwill and other intangible assets            
Balance of finite-lived intangible assets 3,500,000 3,500,000   $ 3,500,000   $ 5,900,000
Intangible assets fair value   3,500,000        
Impairment expense $ 0 $ 2,400,000 $ 0      
Pelican Therapeutics, Inc. | In-process R&D.            
Goodwill and other intangible assets            
Finite-lived intangible assets acquired         $ 5,900,000