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Consolidated Statements of Cash Flows - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Cash Flows from Operating Activities    
Net loss $ (35,400,807) $ (26,381,389)
Adjustments to reconcile net loss to net cash used in operating activities:    
Goodwill impairment loss 1,452,338 0
In-process R&D impairment loss 2,366,000  
Depreciation and amortization 607,667 333,152
Noncash lease expense 83,809 95,600
Noncash interest expense 21,970 17,972
Noncash investor relations expense   66,767
Stock-based compensation 6,168,981 6,377,857
Change in fair value of common stock warrants (22,758) 1,012,167
Change in fair value of contingent consideration 430,000 1,199,000
Unrealized loss (gain) on investments 842,538 (44,871)
Increase (decrease) in cash arising from changes in assets and liabilities:    
Accounts receivable 110,111 (140,559)
Prepaid expenses and other current assets (1,060,915) (1,419,395)
Grant receivable (1,318,359)  
Other assets (12,193,540)  
Accounts payable (126,937) (452,778)
Accrued expenses and other liabilities 929,023 (223,882)
Deferred revenue (806,217) (2,769,101)
Deferred tax liability (145,974)  
Other long-term liabilities 17,286 36,243
Deposits (83,122) 271,858
Net Cash Used in Operating Activities (38,128,906) (22,021,359)
Cash Flows from Investing Activities    
Purchase of short-term investments (66,960,279) (105,925,802)
Sale of short-term investments 78,635,257 10,842,157
Purchase of property and equipment (1,904,713) (337,972)
Proceeds from disposal of property and equipment   2,168
Net Cash Provided by (Used in) Investing Activities 9,770,265 (95,419,449)
Cash Flows from Financing Activities    
Proceeds from public offering of common stock and warrants, net of issuance costs   6,600,971
Proceeds from the issuance of common stock 26,304,282 117,373,495
Proceeds from exercise of stock options 27,261  
Proceeds from exercise of warrants   675,675
Stock issuance costs (658,184) (3,103,833)
Cash paid for fractional shares in connection with reverse stock split   (97,052)
Payment of contingent consideration   (2,005,000)
Proceeds from PPP loan   702,000
Repayment of PPP loan   (702,000)
Repayments on principal of finance lease (183,010) (115,199)
Net Cash Provided by Financing Activities 25,490,349 119,329,057
Effect of exchange rate changes on cash and cash equivalents (9,719) 3,754
Net Change in Cash and Cash Equivalents (2,878,011) 1,892,003
Cash and Cash Equivalents - Beginning of Period 10,931,890 9,039,887
Cash and Cash Equivalents - End of Period 8,053,879 10,931,890
Supplemental Disclosure for Cash Flow Information:    
Right-of-use assets obtained on operating lease commencements 88,596 75,244
Right-of-use assets obtained on operating lease modifications 37,767  
Right-of-use assets obtained on financing lease commencements $ 408,677 173,822
Supplemental disclosure of non-cash investing and financing activities:    
Allocation of proceeds from public offering to warrant liabilities   2,494,823
Cashless exercise of warrants classified as liabilities   2,766,647
Cashless exchange of warrants classified as liabilities   $ 773,330