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Stockholders' Equity - Equity Compensation Plan - Narrative (Details) - shares
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2016
Dec. 31, 2009
Oct. 31, 2018
Jun. 30, 2017
Dec. 31, 2015
Jun. 30, 2014
Apr. 30, 2011
Mar. 31, 2011
Stockholders' Equity                      
Granted 1,674,153 1,167,749                  
Forfeited 79,478                    
Outstanding stock options 2,954,315 1,480,139 437,603                
Dividend yield                      
Stockholders' Equity                      
Annual interest on outstanding balance 0.00%                    
2009 Stock Incentive Plan                      
Stockholders' Equity                      
Number of shares authorized         21,739         65,217 21,739
Expiration term         10 years            
Common shares available for issuance                   86,957  
Outstanding stock options 2,622 6,378                  
2014 Stock Option Plan                      
Stockholders' Equity                      
Number of shares authorized                 50,000    
Stock Incentive Plan, shares authorized increased               60,000      
Outstanding stock options 21,368 30,354                  
2009 and 2014 Plans                      
Stockholders' Equity                      
Granted       300,000              
2017 Stock Option Plan                      
Stockholders' Equity                      
Number of shares authorized             500,000        
Outstanding stock options 38,227 42,932                  
2018 Stock Option Plan                      
Stockholders' Equity                      
Number of shares authorized           571,428          
Increase in the number of shares available for grant     571,428                
Common shares available for issuance 358,897                    
Outstanding stock options 2,847,755 1,400,475