Stockholders' Equity - Common Stock Warrants - Narratives (Details) - $ / shares			1 Months Ended	12 Months Ended
	Nov. 26, 2018	May 07, 2018	Jan. 31, 2021	Dec. 31, 2021	Dec. 31, 2020	Jan. 21, 2020
January 2020 Offering
Stockholders' Equity
Number of shares of common stock issuable through warrants						1,428,571
Common stock warrants
Stockholders' Equity
Warrants exercised			31,000	0	1,959,735
Warrants expired				42,556	0
Warrants exchanged				0	470,238
Number of shares of common stock each warrant is exercisable into			1
Exercise price			$ 5.78
Expiration term			2 years
Warrants outstanding				9,357
Common stock warrants | November 2018 Offering
Stockholders' Equity
Warrants issued	657,142
Number of shares of common stock each warrant is exercisable into	1
Exercise price	$ 11.55
Expiration term	5 years
Common stock warrants | May 2018 Offering
Stockholders' Equity
Number of shares of common stock issuable through warrants		1,357,142
Number of shares of common stock each warrant is exercisable into		1
Exercise price		$ 11.09
Common stock issued for conversion of warrants		1,026,785
Expiration term		5 years
Pre-funded warrant | May 2018 Offering
Stockholders' Equity
Exercise price		$ 0.07