Goodwill and In-process R&D (Details) - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2017
Goodwill and In-Process R&D
Goodwill accumulated impairment	$ 2,200,000	$ 700,000
Goodwill impairment loss	1,452,338	0
Impairment loss	2,366,000
Goodwill, beginning of period	1,452,338
Goodwill impairment loss	(1,452,338)	0
Goodwill, end of period		1,452,338
Intangible assets beginning balance	5,866,000
Impairment loss	(2,366,000)
Intangible assets, ending balance	3,500,000	5,866,000
Intangible assets fair value	3,500,000
In-process R&D
Goodwill and In-Process R&D
Impairment loss	2,366,000	0.0
Change in finite-lived intangible assets		0
Intangible assets beginning balance	5,866,000
Impairment loss	(2,366,000)	(0.0)
Intangible assets, ending balance	3,500,000	$ 5,866,000
Intangible assets fair value	$ 3,500,000
Pelican Therapeutics, Inc.
Goodwill and In-Process R&D
Goodwill acquired			$ 2,200,000
Pelican Therapeutics, Inc. | In-process R&D
Goodwill and In-Process R&D
Finite-lived intangible assets acquired			$ 5,900,000