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Net Loss Per Share - Reconciliation of Net Loss (Details) - USD ($)
3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Net Loss Per Share    
Net loss $ (7,623,140) $ (6,373,420)
Net loss: Non-controlling interest (90,962) (81,314)
Net loss attributable to Heat Biologics, Inc. $ (7,532,178) $ (6,292,106)
Weighted Average Number of Shares Outstanding, Basic and Diluted 24,199,916 8,183,154
Net loss per share, basic and diluted $ (0.31) $ (0.77)