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Basis of Presentation and Significant Accounting Policies (Details) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Mar. 07, 2017
Dec. 31, 2016
Noncontrolling Interest [Line Items]            
Accumulated deficit $ 65,714,314   $ 65,714,314     $ 57,004,655
Net loss 2,300,807 $ 1,616,946 8,709,659 $ 9,101,770    
Grant received for preclinical activities from CPRIT 500,000   900,000      
Non-controlling interest $ 203,371 $ 47,042 344,328 $ 329,471    
Pelican Therapeutics, Inc. [Member]            
Noncontrolling Interest [Line Items]            
Net loss     $ (100,000)      
Percentage of voting interests acquired in acquisition 80.00%   80.00%   80.00%  
Grant received for preclinical activities from CPRIT     $ 15,200,000      
Non-controlling interest $ 164,802   $ 179,253      
Heat Biologics I, Inc. [Member]            
Noncontrolling Interest [Line Items]            
Ownership interest in subsidiary 92.50%   92.50%     92.50%
Non-controlling interest $ 38,569   $ 165,075