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Consolidated Statements of Cash Flows - USD ($)
6 Months Ended
Jun. 30, 2016
Jun. 30, 2015
Cash Flows from Operating Activities    
Net loss $ (7,767,253) $ (8,929,615)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 65,553 53,937
Amortization of deferred financing costs and debt issuance costs 51,489 50,074
Amortization of held to maturity investment premium 32,733 59,882
Stock-based compensation 341,756 786,847
Increase (decrease) in cash arising from changes in assets and liabilities:    
Prepaid expenses, restricted cash and other current assets 434,725 23,202
Deposits (50,000)
Related party receivable (27,000) (9,375)
Accounts payable (1,523,093) (569,974)
Accrued expenses and other payables (748,775) 362,523
Other long term liabilities 247,017 12,228
Net Cash Used in Operating Activities (8,892,848) (8,210,271)
Cash Flows from Investing Activities    
Proceeds from maturities of short-term investments 6,656,910 12,967,509
Purchases of short term investments (10,241,275)
Purchase of property and equipment (43,501) (103,369)
Net Cash Provided by Investing Activities 6,613,409 2,622,865
Cash Flows from Financing Activities    
Proceeds from public offering, net of underwriting discounts 6,287,250 11,400,870
Stock issuance costs (190,768) (302,461)
Proceeds from long term debt 2,242,575
Payments on long term debt (1,613,125)
Net Cash Provided by Financing Activities 4,483,357 13,340,984
Effect of exchange rate changes on cash and cash equivalents (28,481) (16,487)
Net Increase in Cash and Cash Equivalents 2,175,437 7,737,091
Cash and Cash Equivalents - Beginning of Period 4,939,955 3,714,304
Cash and Cash Equivalents - End of Period 7,115,392 11,451,395
Supplemental Disclosure for Cash Flow Information    
Interest paid $ 208,465 $ 98,430