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Consolidated Statements of Cash Flows - USD ($)
9 Months Ended 12 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Dec. 31, 2014
Dec. 31, 2013
Cash Flows from Operating Activities        
Net loss $ (14,357,325) $ (8,508,592) $ (12,243,211) $ (6,609,864)
Adjustments to reconcile net loss to net cash used in operating activities:        
Depreciation 84,373 41,850 66,895 6,348
Amortization of debt issuance costs 75,818 13,848 37,556 28,229
Amortization of bond premium $ 102,618 137,897 173,204 50,781
Re-measurement of fair value of stock warrants liability 7,263 7,263 30,440
Stock based compensation $ 1,046,086 722,358 1,066,443 571,924
Increase (decrease) in cash arising from changes in assets and liabilities:        
Related party receivable (9,375) (18,446) (23,696) (15,375)
Prepaid expenses and other current assets (157,440) 318,275 203,411 (1,008,202)
Restricted cash     (99,877) $ 24,962
Deposits (50,000) (10,478) (10,478)
Accounts payable (385,161) 28,561 715,509 $ 146,446
Accrued expenses and other payables 1,260,355 $ (56,888) 302,918 373,842
Other long term liabilities $ 12,228    
Accrued interest $ (25,364) (25,364) 11,601
Net Cash Used in Operating Activities $ (12,377,823) (7,349,716) (9,829,427) $ (6,388,868)
Cash Flows from Investing Activities        
Proceeds from maturities of short term investments 14,943,468 13,827,773 18,623,826
Purchases of short term investments (11,090,091) (8,783,623) (12,198,847) $ (17,347,946)
Purchases of property and equipment (106,838) (452,444) (458,676) (49,319)
Net Cash Provided by Investing Activities 3,746,539 $ 4,591,706 $ 5,966,303 (17,397,265)
Cash Flows from Financing Activities        
Initial public offering price     $ 25,110,000
Proceeds from long term debt, net     $ 2,972,500
Payments on notes payable     $ (925,000)
Issuance of convertible notes payable, net of issuance costs     (197,099)
Proceeds from March 2015 public offering, net of underwriting discounts $ 11,400,870 540
Proceeds from the exercise of stock options $ 37,719 $ 37,936 54,042
Proceeds from issuance of long term debt $ 2,242,575 $ 1,435,283 200,000
Payments on long term debt (145,161)    
Stock issuance costs (302,461) (944,478)
Net Cash Provided by Financing Activities 13,195,823 $ 1,473,002 $ 3,010,436 28,348,095
Effect of exchange rate changes on cash and cash equivalents (67,905)    
Net (Decrease) Increase in Cash and Cash Equivalents 4,496,634 $ (1,285,008) (852,688) 4,561,962
Cash and Cash Equivalents - Beginning of Period 3,714,304 4,566,992 4,566,992 5,030
Cash and Cash Equivalents - End of Period 8,210,938 3,281,984 3,714,304 4,566,992
Supplemental Disclosure for Cash Flow Information        
Interest paid $ 257,339 8,138 $ 32,025 60,922
Supplemental Schedule of Noncash Investing and Financing Activities        
Beneficial conversion charge     2,300,000
Non-cash conversion of preferred stock into common stock     386
Preferred conversion of preferred stock into common stock     $ 361,668
Cashless exercise of stock warrants $ 452,874 $ 452,874
Issuance of warrants     $ 323,021
Series B-1 Preferred Stock [Member]        
Cash Flows from Operating Activities        
Net loss    
Cash Flows from Financing Activities        
Issuance of preferred stock     $ 5,050,090
Series A Preferred Stock [Member]        
Cash Flows from Operating Activities        
Net loss