Number of shares issued during the period for cashless exercise of warrants, transaction two.

No definition available.

Name:	htbx_CashlessExerciseOfWarrantsSharesTransactionTwo
Namespace Prefix:	htbx_
Data Type:	xbrli:sharesItemType
Balance Type:	na
Period Type:	duration

- Definition

Debt Instrument Annual Principal Payment Pecentage

+ References

No definition available.

+ Details

Name:	htbx_DebtInstrumentAnnualPrincipalPaymentPecentage
Namespace Prefix:	htbx_
Data Type:	num:percentItemType
Balance Type:	na
Period Type:	instant

- Definition

DebtInstrumentPeriodicPaymentInterestPercent

+ References

No definition available.

+ Details

Name:	htbx_DebtInstrumentPeriodicPaymentInterestPercent
Namespace Prefix:	htbx_
Data Type:	num:percentItemType
Balance Type:	na
Period Type:	duration

- Definition

Number Of Warrants Post Reverse Stock Split

+ References

No definition available.

+ Details

Name:	htbx_NumberOfWarrantsPostReverseStockSplit
Namespace Prefix:	htbx_
Data Type:	xbrli:integerItemType
Balance Type:	na
Period Type:	duration

- Definition

Preferred Stock Shares Purchased By Issuance Of Warrant

+ References

No definition available.

+ Details

Name:	htbx_PreferredStockSharesPurchasedByIssuanceOfWarrant
Namespace Prefix:	htbx_
Data Type:	xbrli:sharesItemType
Balance Type:	na
Period Type:	instant

- Definition

Exercise price of the warrants.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher SEC
-Name Regulation S-X (SX)
-Number 210
-Article 12
-Section 13
-Sentence Column A

+ Details

Name:	invest_InvestmentWarrantsExercisePrice
Namespace Prefix:	invest_
Data Type:	num:perShareItemType
Balance Type:	na
Period Type:	duration

- Definition

Expiration date of warrants held.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher SEC
-Name Regulation S-X (SX)
-Number 210
-Article 12
-Section 13
-Sentence Column A

+ Details

Name:	invest_InvestmentWarrantsExpirationDate
Namespace Prefix:	invest_
Data Type:	xbrli:dateItemType
Balance Type:	na
Period Type:	duration

- Definition

Exercise price per share or per unit of warrants or rights outstanding.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 235
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.4-08.(i)(4))
-URI http://asc.fasb.org/extlink&oid=26873400&loc=d3e23780-122690

+ Details

Name:	us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1
Namespace Prefix:	us-gaap_
Data Type:	num:perShareItemType
Balance Type:	na
Period Type:	instant

- Definition

Number of securities into which the class of warrant or right may be converted. For example, but not limited to, 500,000 warrants may be converted into 1,000,000 shares.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 235
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.4-08.(i)(2))
-URI http://asc.fasb.org/extlink&oid=26873400&loc=d3e23780-122690

+ Details

Name:	us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
Namespace Prefix:	us-gaap_
Data Type:	xbrli:sharesItemType
Balance Type:	na
Period Type:	instant

- Definition

Amount of long-term debt before deduction of unamortized discount or premium. Includes, but is not limited to, notes payable, bonds payable, commercial loans, mortgage loans, convertible debt, subordinated debt and other types of debt, with initial maturities beyond one year or the normal operating cycle, if longer.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.22)
-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher SEC
-Name Regulation S-X (SX)
-Number 210
-Section 02
-Paragraph 20
-Article 5

Reference 3: http://www.xbrl.org/2003/role/presentationRef
-Publisher SEC
-Name Regulation S-X (SX)
-Number 210
-Section 03
-Paragraph 16
-Article 9

+ Details

Name:	us-gaap_DebtInstrumentCarryingAmount
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Amount of assets pledged to secure a debt instrument.

+ References

+ Details

Name:	us-gaap_DebtInstrumentCollateralAmount
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	instant

- Definition

Face (par) amount of debt instrument at time of issuance.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 835
-SubTopic 30
-Section 55
-Paragraph 8
-URI http://asc.fasb.org/extlink&oid=34725769&loc=d3e28878-108400

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 835
-SubTopic 30
-Section 45
-Paragraph 2
-URI http://asc.fasb.org/extlink&oid=6451184&loc=d3e28551-108399

+ Details

Name:	us-gaap_DebtInstrumentFaceAmount
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Description of the frequency of periodic payments (monthly, quarterly, annual).

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 942
-SubTopic 470
-Section 50
-Paragraph 3
-Subparagraph (c)
-URI http://asc.fasb.org/extlink&oid=6479336&loc=d3e64711-112823

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.22)
-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

+ Details

Name:	us-gaap_DebtInstrumentFrequencyOfPeriodicPayment
Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration

- Definition

Maximum contractual interest rate for funds borrowed, under the debt agreement.

+ References

+ Details

Name:	us-gaap_DebtInstrumentInterestRateStatedPercentageRateRangeMaximum
Namespace Prefix:	us-gaap_
Data Type:	num:percentItemType
Balance Type:	na
Period Type:	duration

- Definition

Minimum contractual interest rate for funds borrowed, under the debt agreement.

+ References

+ Details

Name:	us-gaap_DebtInstrumentInterestRateStatedPercentageRateRangeMinimum
Namespace Prefix:	us-gaap_
Data Type:	num:percentItemType
Balance Type:	na
Period Type:	duration

- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

+ Details

Name:	us-gaap_DebtInstrumentLineItems
Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration

- Definition

Date when the debt instrument is scheduled to be fully repaid, in CCYY-MM-DD format.

+ References

+ Details

Name:	us-gaap_DebtInstrumentMaturityDate
Namespace Prefix:	us-gaap_
Data Type:	xbrli:dateItemType
Balance Type:	na
Period Type:	duration

- Definition

Period of time between issuance and maturity of debt instrument, in PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

+ References

No definition available.

+ Details

Name:	us-gaap_DebtInstrumentTerm
Namespace Prefix:	us-gaap_
Data Type:	xbrli:durationItemType
Balance Type:	na
Period Type:	duration

- Definition

The amount of debt discount that was originally recognized at the issuance of the instrument that has yet to be amortized.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 835
-SubTopic 30
-Section 45
-Paragraph 1A
-URI http://asc.fasb.org/extlink&oid=6451184&loc=d3e28541-108399

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 835
-SubTopic 30
-Section 55
-Paragraph 8
-URI http://asc.fasb.org/extlink&oid=34725769&loc=d3e28878-108400

+ Details

Name:	us-gaap_DebtInstrumentUnamortizedDiscount
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	instant

- Definition

Weighted average interest rate of debt outstanding.

+ References

No definition available.

+ Details

Name:	us-gaap_DebtWeightedAverageInterestRate
Namespace Prefix:	us-gaap_
Data Type:	num:percentItemType
Balance Type:	na
Period Type:	instant

- Definition

Amount of the cost of borrowed funds accounted for as interest expense for debt.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 225
-SubTopic 10
-Section S99
-Paragraph 2
-Subparagraph (SX 210.5-03.8)
-URI http://asc.fasb.org/extlink&oid=26872669&loc=d3e20235-122688

+ Details

Name:	us-gaap_InterestExpenseDebt
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

- Definition

Including the current and noncurrent portions, aggregate carrying value as of the balance sheet date of loans payable (with maturities initially due after one year or beyond the operating cycle if longer).

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 942
-SubTopic 210
-Section S99
-Paragraph 1
-Subparagraph (SX 210.9-03.16)
-URI http://asc.fasb.org/extlink&oid=6876686&loc=d3e534808-122878

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 944
-SubTopic 210
-Section S99
-Paragraph 1
-Subparagraph (SX 210.7-03.16(a)(2))
-URI http://asc.fasb.org/extlink&oid=6879938&loc=d3e572229-122910

Reference 3: http://www.xbrl.org/2003/role/presentationRef
-Publisher SEC
-Name Regulation S-X (SX)
-Number 210
-Section 02
-Paragraph 19, 20, 22
-Article 5

+ Details

Name:	us-gaap_LoansPayable
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

The cash outflow during the period from the repayment of aggregate short-term and long-term debt. Excludes payment of capital lease obligations.

+ References

No definition available.

+ Details

Name:	us-gaap_RepaymentsOfDebt
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

- Definition

The cash outflow to repay long-term debt that is wholly or partially secured by collateral. Excludes repayments of tax exempt secured debt.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 15
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=56944662&loc=d3e3291-108585

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Glossary Financing Activities
-URI http://asc.fasb.org/extlink&oid=6513228

+ Details

Name:	us-gaap_RepaymentsOfSecuredDebt
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

- Definition

Ratio applied to the conversion of stock split, for example but not limited to, one share converted to two or two shares converted to one.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 505
-SubTopic 10
-Section S99
-Paragraph 4
-Subparagraph (SAB TOPIC 4.C)
-URI http://asc.fasb.org/extlink&oid=27012166&loc=d3e187143-122770

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Glossary Stock Split
-URI http://asc.fasb.org/extlink&oid=6525746

+ Details

Name:	us-gaap_StockholdersEquityNoteStockSplitConversionRatio1
Namespace Prefix:	us-gaap_
Data Type:	xbrli:pureItemType
Balance Type:	na
Period Type:	duration

- Details

Name:	us-gaap_AwardTypeAxis=us-gaap_WarrantMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_LongtermDebtTypeAxis=us-gaap_SecuredDebtMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_StatementClassOfStockAxis=us-gaap_CommonStockMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_RangeAxis=us-gaap_MaximumMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentAxis=htbx_NorthCarolinaBiotechnologyCenterLoanAgreementMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_StatementClassOfStockAxis=us-gaap_SeriesAPreferredStockMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentAxis=htbx_LoanAndSecurityAgreementTrancheaMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentAxis=htbx_LoanAndSecurityAgreementTermLoanBMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentAxis=htbx_LoanAndSecurityAgreementMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentAxis=htbx_LoanAndSecurityAgreementSecondAmendmentMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentAxis=htbx_TrancheOneLoanMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentAxis=htbx_TrancheTwoLoanMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentAxis=htbx_TrancheThreeLoanMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_StatementScenarioAxis=us-gaap_ScenarioForecastMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentAxis=htbx_TrancheFourLoanMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentAxis=htbx_TrancheOneAndTwoLoanMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

Notes Payable (Narrative) (Details)	1 Months Ended							3 Months Ended		9 Months Ended		12 Months Ended
Notes Payable (Narrative) (Details)	Sep. 30, 2014 shares	Aug. 31, 2013 USD ($)	Jul. 31, 2013	Jan. 31, 2013	Aug. 31, 2012 $ / shares	Dec. 31, 2011	Oct. 31, 2011	Sep. 30, 2015 USD ($)	Sep. 30, 2014 USD ($)	Sep. 30, 2015 USD ($)	Sep. 30, 2014 USD ($)	Dec. 31, 2014 USD ($)	Aug. 31, 2014 USD ($) $ / shares shares	Feb. 28, 2014 shares	Dec. 31, 2013 shares	Dec. 14, 2013	Jan. 10, 2013 USD ($)	Dec. 31, 2012 shares	Aug. 07, 2012 USD ($) shares	Oct. 20, 2011 USD ($)
Debt Instrument [Line Items]
Debt instrument, face amount																				$ 950,000
Maturity date							Oct. 31, 2019
Reverse stock split, conversion ratio												0.4348
Warrant [Member]
Debt Instrument [Line Items]
Number of shares of common stock issuable through warrants \| shares															20,549			20,549
Debt discount												$ 323,021
Number of shares issued from cashless exercise of warrant \| shares	17,664
Secured Loan - Square 1 Bank [Member]
Debt Instrument [Line Items]
Debt instrument, amount outstanding								$ 5,250,000		$ 5,250,000
Term of loan												42 months
Number of shares of common stock issuable through warrants \| shares													52,695
Debt instrument, minimum interest rate										3.05%		3.05%
Debt instrument, maximum interest rate										6.30%		6.30%
Repayment of principal made during period								145,161	$ 145,161	$ 0	$ 0	$ 0
Interest paid during period								83,090	$ 0	181,520	$ 0	24,150
Exercise price of warrants \| $ / shares													$ 4.27
Secured Loan - Square 1 Bank [Member] \| Warrant [Member]
Debt Instrument [Line Items]
Debt discount												323,021	$ 323,021
Secured Loan - Square 1 Bank [Member] \| Common Stock [Member]
Debt Instrument [Line Items]
Number of shares issued from cashless exercise of warrant \| shares	17,664
Secured Loan - Square 1 Bank [Member] \| Maximum [Member]
Debt Instrument [Line Items]
Debt instrument, face amount													$ 7,500,000
North Carolina Biotechnology Center Loan Agreement [Member]
Debt Instrument [Line Items]
Annual installments																5.00%
North Carolina Biotechnology Center Loan Agreement [Member] \| Series A Preferred Stock [Member]
Debt Instrument [Line Items]
Warrant expiration date						Dec. 13, 2021
Loan And Security Agreement Tranche A [Member]
Debt Instrument [Line Items]
Debt instrument, face amount																			$ 1,000,000
Accrues interest, annual																			6.00%
Accrues interest, monthly					3.00%
Term of loan					36 months
Periodic payments, frequency					Monthly
Loan And Security Agreement Term Loan B [Member]
Debt Instrument [Line Items]
Annual installments		5.00%											5.00%
Accrues interest, annual																			4.25%
Repayment of note payable and bank loan		$ 725,000
Loan And Security Agreement Term Loan B [Member] \| Maximum [Member]
Debt Instrument [Line Items]
Debt instrument, face amount																			$ 225,000
Loan And Security Agreement [Member]
Debt Instrument [Line Items]
Number Of Warrants Post Reverse Stock Split			7,609
Number of shares of common stock issuable through warrants \| shares														3,072
Loan And Security Agreement [Member] \| Series A Preferred Stock [Member]
Debt Instrument [Line Items]
Preferred stock shares purchased by warrant issued \| shares																			17,500
Exercise price of warrants \| $ / shares					$ 4.83
Warrant expiration date					Aug. 07, 2022
Loan And Security Agreement Second Amendment [Member]
Debt Instrument [Line Items]
Outstanding loan																	$ 200,000
Collateral amount																	200,000
Maturity date				Jan. 09, 2014
Loan And Security Agreement Second Amendment [Member] \| Maximum [Member]
Debt Instrument [Line Items]
Debt instrument, face amount																	$ 200,000
Tranche 1 Loan [Member] \| Secured Loan - Square 1 Bank [Member]
Debt Instrument [Line Items]
Debt instrument, face amount													$ 1,500,000
Debt instrument, amount outstanding								1,500,000		1,500,000		1,500,000
Tranche 2 Loan [Member] \| Secured Loan - Square 1 Bank [Member]
Debt Instrument [Line Items]
Debt instrument, face amount													1,500,000
Debt instrument, amount outstanding								1,500,000		1,500,000		1,500,000
Tranche 3 Loan [Member] \| Secured Loan - Square 1 Bank [Member]
Debt Instrument [Line Items]
Debt instrument, face amount													2,250,000
Debt instrument, amount outstanding								$ 2,250,000		$ 2,250,000
Tranche 3 Loan [Member] \| Secured Loan - Square 1 Bank [Member] \| Scenario, Forecast [Member]
Debt Instrument [Line Items]
Debt instrument, face amount													2,250,000
Tranche 4 Loan [Member] \| Secured Loan - Square 1 Bank [Member]
Debt Instrument [Line Items]
Debt instrument, face amount													2,250,000
Tranche 4 Loan [Member] \| Secured Loan - Square 1 Bank [Member] \| Scenario, Forecast [Member]
Debt Instrument [Line Items]
Debt instrument, face amount													$ 2,250,000
Tranche 1 and 2 Loan [Member] \| Secured Loan - Square 1 Bank [Member]
Debt Instrument [Line Items]
Debt instrument, amount outstanding												$ 3,000,000