2.4.0.8 Html 272 386 1 false 62 0 false 5 false false R1.htm 001 - Document - Document and Entity Information Sheet http://www.heatbio.com/role/DocumentAndEntityInformation Document and Entity Information true false R2.htm 002 - Statement - Consolidated Balance Sheets Sheet http://www.heatbio.com/role/ConsolidatedBalanceSheets Consolidated Balance Sheets false false R3.htm 003 - Statement - Consolidated Balance Sheets (Parenthetical) Sheet http://www.heatbio.com/role/ConsolidatedBalanceSheetsParenthetical Consolidated Balance Sheets (Parenthetical) false false R4.htm 004 - Statement - Consolidated Statements of Operations Sheet http://www.heatbio.com/role/ConsolidatedStatementsOfOperations Consolidated Statements of Operations false false R5.htm 005 - Statement - Consolidated Statement of Stockholders Equity (Deficit) Sheet http://www.heatbio.com/role/ConsolidatedStatementOfStockholdersEquityDeficit Consolidated Statement of Stockholders Equity (Deficit) false false R6.htm 006 - Statement - Consolidated Statement of Stockholders Equity (Deficit) (Parenthetical) Sheet http://www.heatbio.com/role/ConsolidatedStatementOfStockholdersEquityDeficitParenthetical Consolidated Statement of Stockholders Equity (Deficit) (Parenthetical) false false R7.htm 007 - Statement - Consolidated Statements of Cash Flows Sheet http://www.heatbio.com/role/ConsolidatedStatementsOfCashFlows Consolidated Statements of Cash Flows false false R8.htm 101 - Disclosure - Organization Sheet http://www.heatbio.com/role/Organization Organization false false R9.htm 102 - Disclosure - Summary of Significant Accounting Policies Sheet http://www.heatbio.com/role/SummaryOfSignificantAccountingPolicies Summary of Significant Accounting Policies false false R10.htm 103 - Disclosure - Discontinued Operations Sheet http://www.heatbio.com/role/DiscontinuedOperations Discontinued Operations false false R11.htm 104 - Disclosure - Investments Sheet http://www.heatbio.com/role/Investments Investments false false R12.htm 105 - Disclosure - Property and Equipment Sheet http://www.heatbio.com/role/PropertyAndEquipment Property and Equipment false false R13.htm 106 - Disclosure - Accrued Expenses Sheet http://www.heatbio.com/role/AccruedExpenses Accrued Expenses false false R14.htm 107 - Disclosure - Debt Issuance Costs Sheet http://www.heatbio.com/role/DebtIssuanceCosts Debt Issuance Costs false false R15.htm 108 - Disclosure - Convertible Notes Payable Notes http://www.heatbio.com/role/ConvertibleNotesPayable Convertible Notes Payable false false R16.htm 109 - Disclosure - Notes Payable Notes http://www.heatbio.com/role/NotesPayable Notes Payable false false R17.htm 110 - Disclosure - License Agreements Sheet http://www.heatbio.com/role/LicenseAgreements License Agreements false false R18.htm 111 - Disclosure - Stock Warrants Liability Sheet http://www.heatbio.com/role/StockWarrantsLiability Stock Warrants Liability false false R19.htm 112 - Disclosure - Stockholders' Equity (Deficit) Sheet http://www.heatbio.com/role/StockholdersEquityDeficit Stockholders' Equity (Deficit) false false R20.htm 113 - Disclosure - Income Tax Sheet http://www.heatbio.com/role/IncomeTax Income Tax false false R21.htm 114 - Disclosure - Commitments and Contingencies Sheet http://www.heatbio.com/role/CommitmentsAndContingencies Commitments and Contingencies false false R22.htm 115 - Disclosure - Related Party Sheet http://www.heatbio.com/role/RelatedParty Related Party false false R23.htm 116 - Disclosure - Net Loss Per Share Sheet http://www.heatbio.com/role/NetLossPerShare Net Loss Per Share false false R24.htm 117 - Disclosure - Subsequent Events Sheet http://www.heatbio.com/role/SubsequentEvents Subsequent Events false false R25.htm 202 - Disclosure - Summary of Significant Accounting Policies (Policies) Sheet http://www.heatbio.com/role/SummaryOfSignificantAccountingPoliciesPolicies Summary of Significant Accounting Policies (Policies) false false R26.htm 302 - Disclosure - Summary of Significant Accounting Policies (Tables) Sheet http://www.heatbio.com/role/SummaryOfSignificantAccountingPoliciesTables Summary of Significant Accounting Policies (Tables) false false R27.htm 304 - Disclosure - Investments (Tables) Sheet http://www.heatbio.com/role/InvestmentsTables Investments (Tables) false false R28.htm 305 - Disclosure - Property and Equipment (Tables) Sheet http://www.heatbio.com/role/PropertyAndEquipmentTables Property and Equipment (Tables) false false R29.htm 306 - Disclosure - Accrued Expenses (Tables) Sheet http://www.heatbio.com/role/AccruedExpensesTables Accrued Expenses (Tables) false false R30.htm 310 - Disclosure - License Agreements (Tables) Sheet http://www.heatbio.com/role/LicenseAgreementsTables License Agreements (Tables) false false R31.htm 311 - Disclosure - Stock Warrants Liability (Tables) Sheet http://www.heatbio.com/role/StockWarrantsLiabilityTables Stock Warrants Liability (Tables) false false R32.htm 312 - Disclosure - Stockholders' Equity (Deficit) (Tables) Sheet http://www.heatbio.com/role/StockholdersEquityDeficitTables Stockholders' Equity (Deficit) (Tables) false false R33.htm 313 - Disclosure - Income Tax (Tables) Sheet http://www.heatbio.com/role/IncomeTaxTables Income Tax (Tables) false false R34.htm 316 - Disclosure - Net Loss Per Share (Tables) Sheet http://www.heatbio.com/role/NetLossPerShareTables Net Loss Per Share (Tables) false false R35.htm 317 - Disclosure - Subsequent Events (Tables) Sheet http://www.heatbio.com/role/SubsequentEventsTables Subsequent Events (Tables) false false R36.htm 40101 - Disclosure - Organization (Details) Sheet http://www.heatbio.com/role/OrganizationDetails Organization (Details) false false R37.htm 40201 - Disclosure - Summary of Significant Accounting Policies (Details) Sheet http://www.heatbio.com/role/SummaryOfSignificantAccountingPoliciesDetails Summary of Significant Accounting Policies (Details) false false R38.htm 40202 - Disclosure - Summary of Significant Accounting Policies (Assumptions Used in Valuation of Warrants) (Details) Sheet http://www.heatbio.com/role/SummaryOfSignificantAccountingPoliciesAssumptionsUsedInValuationOfWarrantsDetails Summary of Significant Accounting Policies (Assumptions Used in Valuation of Warrants) (Details) false false R39.htm 40203 - Disclosure - Summary of Significant Accounting Policies (Schedule of Change in Fair Value of the Level III Common Stock Warrant Liability ) (Details) Sheet http://www.heatbio.com/role/SummaryOfSignificantAccountingPoliciesScheduleOfChangeInFairValueOfLevelIiiCommonStockWarrantLiabilityDetails Summary of Significant Accounting Policies (Schedule of Change in Fair Value of the Level III Common Stock Warrant Liability ) (Details) false false R40.htm 40204 - Disclosure - Summary of Significant Accounting Policies (Schedule of Changes In Fair Value of Level III Stock Warrants Liability) (Details) Sheet http://www.heatbio.com/role/SummaryOfSignificantAccountingPoliciesScheduleOfChangesInFairValueOfLevelIiiStockWarrantsLiabilityDetails Summary of Significant Accounting Policies (Schedule of Changes In Fair Value of Level III Stock Warrants Liability) (Details) false false R41.htm 40301 - Disclosure - Discontinued Operations (Details) Sheet http://www.heatbio.com/role/DiscontinuedOperationsDetails Discontinued Operations (Details) false false R42.htm 40401 - Disclosure - Investments (Schedule of Held-To-Maturity Investments) (Details) Sheet http://www.heatbio.com/role/InvestmentsScheduleOfHeldtomaturityInvestmentsDetails Investments (Schedule of Held-To-Maturity Investments) (Details) false false R43.htm 40501 - Disclosure - Property and Equipment (Schedule of Property and Equipment ) (Details) Sheet http://www.heatbio.com/role/PropertyAndEquipmentScheduleOfPropertyAndEquipmentDetails Property and Equipment (Schedule of Property and Equipment ) (Details) false false R44.htm 40601 - Disclosure - Accrued Expenses (Schedule of Accrued Expenses) (Details) Sheet http://www.heatbio.com/role/AccruedExpensesScheduleOfAccruedExpensesDetails Accrued Expenses (Schedule of Accrued Expenses) (Details) false false R45.htm 40701 - Disclosure - Debt Issuance Costs (Narrative) (Details) Sheet http://www.heatbio.com/role/DebtIssuanceCostsNarrativeDetails Debt Issuance Costs (Narrative) (Details) false false R46.htm 40801 - Disclosure - Convertible Notes Payable (Narrative) (Details) Notes http://www.heatbio.com/role/ConvertibleNotesPayableNarrativeDetails Convertible Notes Payable (Narrative) (Details) false false R47.htm 40901 - Disclosure - Notes Payable (Narrative) (Details) Notes http://www.heatbio.com/role/NotesPayableNarrativeDetails Notes Payable (Narrative) (Details) false false R48.htm 41001 - Disclosure - License Agreements (Schedule of Future Minimum Royalty Payments) (Details) Sheet http://www.heatbio.com/role/LicenseAgreementsScheduleOfFutureMinimumRoyaltyPaymentsDetails License Agreements (Schedule of Future Minimum Royalty Payments) (Details) false false R49.htm 41002 - Disclosure - License Agreements (Narrative) (Details) Sheet http://www.heatbio.com/role/LicenseAgreementsNarrativeDetails License Agreements (Narrative) (Details) false false R50.htm 41101 - Disclosure - Stock Warrants Liability (Details) Sheet http://www.heatbio.com/role/StockWarrantsLiabilityDetails Stock Warrants Liability (Details) false false R51.htm 41201 - Disclosure - Stockholders' Equity (Deficit) (Narrative) (Details) Sheet http://www.heatbio.com/role/StockholdersEquityDeficitNarrativeDetails Stockholders' Equity (Deficit) (Narrative) (Details) false false R52.htm 41202 - Disclosure - Stockholders' Equity (Deficit) (Schedule of Restricted Stock Activity) (Details) Sheet http://www.heatbio.com/role/StockholdersEquityDeficitScheduleOfRestrictedStockActivityDetails Stockholders' Equity (Deficit) (Schedule of Restricted Stock Activity) (Details) false false R53.htm 41203 - Disclosure - Stockholders' Equity (Deficit) (Common Stock Warrants) (Details) Sheet http://www.heatbio.com/role/StockholdersEquityDeficitCommonStockWarrantsDetails Stockholders' Equity (Deficit) (Common Stock Warrants) (Details) false false R54.htm 41204 - Disclosure - Stockholders' Equity (Deficit) (Equity Compensation Plan) (Narrative) (Details) Sheet http://www.heatbio.com/role/StockholdersEquityDeficitEquityCompensationPlanNarrativeDetails Stockholders' Equity (Deficit) (Equity Compensation Plan) (Narrative) (Details) false false R55.htm 41205 - Disclosure - Stockholders' Equity (Deficit) (Schedule of Stock-based Compensation) (Details) Sheet http://www.heatbio.com/role/StockholdersEquityDeficitScheduleOfStockbasedCompensationDetails Stockholders' Equity (Deficit) (Schedule of Stock-based Compensation) (Details) false false R56.htm 41206 - Disclosure - Stockholders' Equity (Deficit) (Schedule of Stock Option Activity) (Details) Sheet http://www.heatbio.com/role/StockholdersEquityDeficitScheduleOfStockOptionActivityDetails Stockholders' Equity (Deficit) (Schedule of Stock Option Activity) (Details) false false R57.htm 41207 - Disclosure - Stockholders' Equity (Deficit) (Schedule of Stock Option Valuation Assumptions) (Details) Sheet http://www.heatbio.com/role/StockholdersEquityDeficitScheduleOfStockOptionValuationAssumptionsDetails Stockholders' Equity (Deficit) (Schedule of Stock Option Valuation Assumptions) (Details) false false R58.htm 41208 - Disclosure - Stockholders' Equity (Deficit) (Summary of Outstandng Stock Options) (Details) Sheet http://www.heatbio.com/role/StockholdersEquityDeficitSummaryOfOutstandngStockOptionsDetails Stockholders' Equity (Deficit) (Summary of Outstandng Stock Options) (Details) false false R59.htm 41209 - Disclosure - Stockholders' Equity (Deficit) (Schedule of Nonvested Stock Option Activity) (Details) Sheet http://www.heatbio.com/role/StockholdersEquityDeficitScheduleOfNonvestedStockOptionActivityDetails Stockholders' Equity (Deficit) (Schedule of Nonvested Stock Option Activity) (Details) false false R60.htm 41301 - Disclosure - Income Tax (Schedule of Income Tax Expense (Benefit)) (Details) Sheet http://www.heatbio.com/role/IncomeTaxScheduleOfIncomeTaxExpenseBenefitDetails Income Tax (Schedule of Income Tax Expense (Benefit)) (Details) false false R61.htm 41302 - Disclosure - Income Tax (Schedule of Income Tax Rate Differences) (Details) Sheet http://www.heatbio.com/role/IncomeTaxScheduleOfIncomeTaxRateDifferencesDetails Income Tax (Schedule of Income Tax Rate Differences) (Details) false false R62.htm 41303 - Disclosure - Income Tax (Schedule of Deferred Tax Assets) (Details) Sheet http://www.heatbio.com/role/IncomeTaxScheduleOfDeferredTaxAssetsDetails Income Tax (Schedule of Deferred Tax Assets) (Details) false false R63.htm 41304 - Disclosure - Income Tax (Narrative) (Details) Sheet http://www.heatbio.com/role/IncomeTaxNarrativeDetails Income Tax (Narrative) (Details) false false R64.htm 41401 - Disclosure - Commitments and Contingencies (Details) Sheet http://www.heatbio.com/role/CommitmentsAndContingenciesDetails Commitments and Contingencies (Details) false false R65.htm 41501 - Disclosure - Related Party (Narrative) (Details) Sheet http://www.heatbio.com/role/RelatedPartyNarrativeDetails Related Party (Narrative) (Details) false false R66.htm 41601 - Disclosure - Net Loss Per Share (Reverse Stock Split) (Details) Sheet http://www.heatbio.com/role/NetLossPerShareReverseStockSplitDetails Net Loss Per Share (Reverse Stock Split) (Details) false false R67.htm 41602 - Disclosure - Net Loss Per Share (Schedule of Antidilutive Securities) (Details) Sheet http://www.heatbio.com/role/NetLossPerShareScheduleOfAntidilutiveSecuritiesDetails Net Loss Per Share (Schedule of Antidilutive Securities) (Details) false false R68.htm 41603 - Disclosure - Net Loss Per Share (Schedule of Reconciliation of Net Loss Applicable to Common Shareholders) (Details) Sheet http://www.heatbio.com/role/NetLossPerShareScheduleOfReconciliationOfNetLossApplicableToCommonShareholdersDetails Net Loss Per Share (Schedule of Reconciliation of Net Loss Applicable to Common Shareholders) (Details) false false R69.htm 41701 - Disclosure - Subsequent Events (Details) Sheet http://www.heatbio.com/role/SubsequentEventsDetails Subsequent Events (Details) false false All Reports Book All Reports Element htbx_PercentageOfOutstandingStockIssuedWithAgreement had a mix of decimals attribute values: 1 3. Element htbx_ProceedsFromIssuanceInitialPublicOfferingNet had a mix of decimals attribute values: -5 0. Element us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate had a mix of decimals attribute values: 1 2. Element us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate had a mix of decimals attribute values: 4 5. Process Flow-Through: 002 - Statement - Consolidated Balance Sheets Process Flow-Through: Removing column 'Dec. 31, 2011' Process Flow-Through: Removing column 'Dec. 31, 2010' Process Flow-Through: Removing column 'Dec. 31, 2009' Process Flow-Through: Removing column 'Dec. 31, 2008' Process Flow-Through: Removing column 'Jun. 09, 2008' Process Flow-Through: Removing column 'Jun. 07, 2008' Process Flow-Through: 003 - Statement - Consolidated Balance Sheets (Parenthetical) Process Flow-Through: 004 - Statement - Consolidated Statements of Operations Process Flow-Through: Removing column '7 Months Ended Dec. 31, 2008' Process Flow-Through: Removing column '12 Months Ended Dec. 31, 2011' Process Flow-Through: Removing column '12 Months Ended Dec. 31, 2009' Process Flow-Through: 006 - Statement - Consolidated Statement of Stockholders Equity (Deficit) (Parenthetical) Process Flow-Through: Removing column '1 Months Ended Sep. 30, 2013' Process Flow-Through: Removing column '1 Months Ended Aug. 31, 2013' Process Flow-Through: Removing column '1 Months Ended Jul. 31, 2013' Process Flow-Through: 007 - Statement - Consolidated Statements of Cash Flows htbx-20131231.xml htbx-20131231.xsd htbx-20131231_cal.xml htbx-20131231_def.xml htbx-20131231_lab.xml htbx-20131231_pre.xml true true