X0303 4 2010-08-25 0 0000887359 AASTROM BIOSCIENCES INC ASTM 0001474713 Urschel Harold C Jr P.O. BOX 376 ANN ARBOR MI 48106 1 0 0 0 Stock Option (right to buy) 1.40 2010-08-25 4 A 0 26000 1.40 A 2020-08-25 Common Stock 26000 26000 D Award of options to purchase common stock that vests exercisable in accordance with the following schedule: (a) with respect to one-third of the total number of underlying shares, on the first anniversary of the grant date (8/24/2010), (b) with respect to an additional one third of the total number of underlying shares, on the second anniversary of the grant date, and (c) with respect to any remaining underlying shares on the third anniversary of the grant date. /s/ Scott Durbin, attorney in fact 2010-08-27