Stock-Based Compensation, Stock Option Activity (Details) - Stock Options [Member]	3 Months Ended
	Mar. 31, 2021 USD ($) $ / shares shares
Number of Shares [Roll Forward]
Options outstanding, beginning balance (in shares) | shares	1,650,897
Granted (in shares) | shares	267,800
Exercised (in shares) | shares	0
Forfeited (in shares) | shares	(19,500)
Expired (in shares) | shares	0
Options outstanding, ending balance (in shares) | shares	1,899,197
Vested and expected to vest (in shares) | shares	1,899,197
Exercisable (in shares) | shares	1,167,963
Weighted Average Exercise Price [Roll Forward]
Options outstanding, beginning balance (in dollars per share) | $ / shares	$ 11.87
Granted (in dollars per share) | $ / shares	2.32
Exercised (in dollars per share) | $ / shares	0
Forfeited (in dollars per share) | $ / shares	23.87
Expired (in dollars per share) | $ / shares	0
Options outstanding, ending balance (in dollars per share) | $ / shares	10.40
Vested and expected to vest (in dollars per share) | $ / shares	10.40
Exercisable (in dollars per share) | $ / shares	$ 15.10
Weighted Average Remaining Contractual Life and Aggregate Intrinsic Value [Abstract]
Options outstanding, weighted average remaining contractual life	7 years 2 months 12 days
Vested and expected to vest, weighted average remaining contractual life	7 years 2 months 12 days
Exercisable, weighted average remaining contractual life	5 years 6 months 7 days
Options outstanding, aggregate intrinsic value | $	$ 1,654,588
Vested and expected to vest, aggregate intrinsic value | $	1,654,588
Exercisable, aggregate intrinsic value | $	157,569
Unamortized Stock Compensation Expense [Abstract]
Unamortized stock compensation expense | $	$ 1,483,195
Period for recognition	3 years