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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2020
Income Taxes [Abstract]  
Statutory to Effective Federal Income Tax Rate Reconciliation
A reconciliation of the statutory U.S. federal income tax rate to the Company’s effective tax rate is as follows:

  
December 31,
 
  
2020
  
2019
 
Federal statutory rate
  
21.0
%
  
21.0
%
State taxes
  
6.7
%
  
21.1
%
Extraordinary gain
  
0.0
%
  
38.0
%
Permanent differences
  
(4.5
)%
  
(4.1
)%
Research and development
  
2.3
%
  
4.1
%
Valuation Allowance
  
(27.1
)%
  
(74.6
)%
Other
  
1.6
%
  
(0.3
)%
Effective tax rate
  
0.0
%
  
5.2
%
Deferred Tax Assets, Net
The tax effects of temporary differences that give rise to significant portions of the deferred tax assets were as follows:

  
December 31,
 
  
2020
  
2019
 
Federal net operating losses
 
$
19,757,859
  
$
16,620,765
 
State net operating losses
  
5,704,791
   
4,653,462
 
Stock options
  
1,687,123
   
2,153,487
 
Restricted stock/warrants
  
–
   
143,841
 
Federal tax credit
  
1,089,138
   
740,040
 
State tax credits
  
752,791
   
657,376
 
Amortization
  
41,695
   
47,811
 
Accrued expense
  
352,642
   
363,617
 
Depreciation
  
721,024
   
719,263
 
Lease liabilities
  
171,543
   
–
 
Other
  
18,098
   
18,098
 
Total gross deferred tax assets
  
30,296,704
   
26,117,760
 
Less valuation allowance
  
(30,142,744
)
  
(26,117,760
)
Net deferred tax assets
 
$
153,960
  
$
–
 
         
Right of use asset
  (153,960)  – 
Total gross deferred tax liabilities
  
(153,960
)
  
–
 
Deferred tax, net
  
–

  
–