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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2020
Income Taxes [Abstract]  
Statutory to Effective Federal Income Tax Rate Reconciliation
A reconciliation of the statutory U.S. federal income tax rate to the Company’s effective tax rate is as follows:

  
December 31,
 
  
2020
  
2019
 
Federal statutory rate
  
21.0
%
  
21.0
%
State taxes
  
6.7
%
  
21.1
%
Extraordinary gain
  
0.0
%
  
38.0
%
Permanent differences
  
(4.5
)%
  
(4.1
)%
Research and development
  
2.3
%
  
4.1
%
Valuation Allowance
  
(27.1
)%
  
(74.6
)%
Other
  
1.6
%
  
(0.3
)%
Effective tax rate
  
0.0
%
  
5.2
%
Deferred Tax Assets, Net
The tax effects of temporary differences that give rise to significant portions of the deferred tax assets were as follows:

  
December 31,
 
  
2020
  
2019
 
Federal net operating losses
 
$
19,757,859
  
$
16,620,765
 
State net operating losses
  
5,704,791
   
4,653,462
 
Stock options
  
1,687,123
   
2,153,487
 
Restricted stock/warrants
  
   
143,841
 
Federal tax credit
  
1,089,138
   
740,040
 
State tax credits
  
752,791
   
657,376
 
Amortization
  
41,695
   
47,811
 
Accrued expense
  
352,642
   
363,617
 
Depreciation
  
721,024
   
719,263
 
Lease liabilities
  
171,543
   
 
Other
  
18,098
   
18,098
 
Total gross deferred tax assets
  
30,296,704
   
26,117,760
 
Less valuation allowance
  
(30,142,744
)
  
(26,117,760
)
Net deferred tax assets
 
$
153,960
  
$
 
         
Right of use asset
  (153,960)   
Total gross deferred tax liabilities
  
(153,960
)
  
 
Deferred tax, net