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Stock-Based Compensation, Stock Option Activity (Details)
3 Months Ended 9 Months Ended
Sep. 30, 2020
USD ($)
$ / shares
shares
Sep. 30, 2020
USD ($)
$ / shares
shares
Unamortized Stock Compensation Expense [Abstract]    
Unamortized stock compensation expense | $ $ 1,424,897 $ 1,424,897
Stock Options [Member]    
Number of Shares [Roll Forward]    
Options outstanding, beginning balance (in shares) | shares   1,421,797
Granted (in shares) | shares 0 319,907
Exercised (in shares) | shares   0
Forfeited (in shares) | shares   (84,227)
Expired (in shares) | shares   (17,724)
Options outstanding, ending balance (in shares) | shares 1,639,753 1,639,753
Vested and expected to vest (in shares) | shares 1,639,753 1,639,753
Exercisable (in shares) | shares 1,066,601 1,066,601
Weighted Average Exercise Price [Roll Forward]    
Options outstanding, beginning balance (in dollars per share) | $ / shares   $ 15.95
Granted (in dollars per share) | $ / shares   1.43
Exercised (in dollars per share) | $ / shares   0
Forfeited (in dollars per share) | $ / shares   41.34
Expired (in dollars per share) | $ / shares   4.69
Options outstanding, ending balance (in dollars per share) | $ / shares $ 11.94 11.94
Vested and expected to vest (in dollars per share) | $ / shares 11.94 11.94
Exercisable (in dollars per share) | $ / shares $ 16.54 $ 16.54
Weighted Average Remaining Contractual Life and Aggregate Intrinsic Value [Abstract]    
Options outstanding, weighted average remaining contractual life   6 years 11 months 1 day
Vested and expected to vest, weighted average remaining contractual life   6 years 11 months 1 day
Exercisable, weighted average remaining contractual life   5 years 7 months 24 days
Options outstanding, aggregate intrinsic value | $ $ 287,063 $ 287,063
Vested and expected to vest, aggregate intrinsic value | $ 287,063 287,063
Exercisable, aggregate intrinsic value | $ $ 0 $ 0
Unamortized Stock Compensation Expense [Abstract]    
Period for recognition   3 years 1 month 24 days