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Stock-Based Compensation (Tables)
12 Months Ended
Dec. 31, 2019
Stock-Based Compensation [Abstract]  
Stock-Based Compensation Expense
The following table summarizes the components of stock-based compensation expense in the consolidated statements of operations and comprehensive loss for the years ended December 31, 2019 and 2018:

 
Year Ended December 31,
 
 
2019
 
2018
 

    
Research and development
 
$
550,605
  
$
46,383
 
General and administrative
  
2,588,448
   
205,564
 
Total
 
$
3,139,053
  
$
251,947
 
Stock Option Activity
The following table summarizes the stock option activity for the Company’ stock option plans for the year ended December 31, 2019:

  
Number
of Shares
  
Weighted Average
Exercise Price
  
Weighted Average
Remaining Contractual
Life in Years
  
Aggregate
Intrinsic Value
 
Balance at January 1, 2019
  
541,117
  
$
7.20
   
4.29
  
$
 
Assumed in connection with merger
  
347,697
  
$
121.52
   
5.67
  
$
 
Granted
  
828,637
  
$
7.43
   
9.35
  
$
 
Exercised
  
  
$
   
  
$
 
Forfeited
  
(295,654
)
 
$
99.27
   
  
$
 
Options outstanding at December 31, 2019
  
1,421,797
  
$
15.95
   
7.09
  
$
 
Vested and expected to vest at December 31, 2019
  
1,421,797
  
$
15.95
   
7.09
  
$
 
Exercisable at December 31, 2019
  
1,000,367
  
$
20.15
   
6.03
  
$
 
Assumptions Used to Value Stock Options Granted
The fair value of options granted during the year ended December 31, 2019 was estimated using the Black-Scholes option valuation model utilizing the following assumptions:

  
Year Ended
 
  
December 31, 2019
 
  
Weighted Average
 
Volatility
  
85% - 94%

Risk-Free Interest Rate
  
1.49% - 2.43%

Expected Term in Years
 
5.54 years 
Dividend Rate