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Condensed Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Operating expenses:        
Research and development expenses $ 2,523,796 $ 8,975,304 $ 15,265,881 $ 16,564,800
General and administrative expenses 3,335,039 4,173,384 8,016,555 8,375,226
Restructuring expenses 6,646,242 0 6,646,242 0
Impairment charges 0 0 2,672,581 0
Total operating expenses 12,505,077 13,148,688 32,601,259 24,940,026
Loss from operations (12,505,077) (13,148,688) (32,601,259) (24,940,026)
Other income (expense):        
Interest income 262,140 168,974 508,779 265,233
Interest expense (434,695) (524,768) (1,425,255) (999,909)
Net loss $ (12,677,632) $ (13,504,482) $ (33,517,735) $ (25,674,702)
Loss per share basic and diluted (in dollars per share) $ (0.41) $ (0.44) $ (1.08) $ (0.86)
Weighted average common shares outstanding basic and diluted (in shares) 31,298,429 30,403,419 31,133,070 29,704,898