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Stock Options, Stock Option Activity (Details)
6 Months Ended
Jun. 30, 2018
USD ($)
$ / shares
shares
Unamortized Stock Compensation Expense [Abstract]  
Unamortized stock compensation expense | $ $ 15,319,731
Period for recognition 1 year 11 months 19 days
Stock Options [Member]  
Number of Shares [Roll Forward]  
Options outstanding, beginning balance (in shares) | shares 6,462,795
Granted (in shares) | shares 2,322,906
Exercised (in shares) | shares (198,300)
Forfeited (in shares) | shares (1,194,835)
Options outstanding, ending balance (in shares) | shares 7,392,566
Vested and expected to vest (in shares) | shares 7,392,566
Exercisable (in shares) | shares 4,183,685
Weighted Average Exercise Price [Roll Forward]  
Options outstanding, beginning balance (in dollars per share) | $ / shares $ 6.50
Granted (in dollars per share) | $ / shares 7.52
Exercised (in dollars per share) | $ / shares 3.64
Forfeited (in dollars per share) | $ / shares 10.35
Options outstanding, ending balance (in dollars per share) | $ / shares 6.28
Vested and expected to vest (in dollars per share) | $ / shares 6.28
Exercisable (in dollars per share) | $ / shares $ 5.54
Weighted Average Remaining Contractual Life and Aggregate Intrinsic Value [Abstract]  
Options outstanding, weighted average remaining contractual life 6 years 5 months 5 days
Vested and expected to vest, weighted average remaining contractual life 6 years 5 months 5 days
Exercisable, weighted average remaining contractual life 6 years 4 days
Options outstanding, aggregate intrinsic value | $ $ 107,730
Vested and expected to vest, aggregate intrinsic value | $ 107,730
Exercisable, aggregate intrinsic value | $ $ 107,730