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Stock Options, Assumptions Used to Value Stock Options and Warrants Granted (Details) - $ / shares
3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Assumptions Used in Determining Fair Value of Stock Options and Warrants Granted [Abstract]        
Volatility 87.82% 85.71% 89.06% 88.93%
Risk-free interest rate 2.27% 1.84% 2.31% 1.89%
Expected term 2 years 6 months 5 years 6 months 22 days 4 years 2 months 26 days 5 years 11 months 26 days
Dividend rate 0.00% 0.00% 0.00% 0.00%
Fair value of option on grant date (in dollars per share) $ 0.58 $ 7.15 $ 5.54 $ 6.73