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Condensed Statements of Cash Flows (Unaudited) - USD ($)
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Cash flows from operating activities:    
Net loss $ (20,840,103) $ (12,170,220)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 1,985,786 1,485,705
Stock-based 401K company common match 40,847 121,620
Depreciation expense 48,542 42,306
Impairment of machinery and equipment 2,672,581 0
Amortization of debt discount 1,039 12,365
Amortization of debt issuance costs 125,355 27,102
Non-cash interest expense 405,278 92,549
Changes in assets and liabilities:    
Prepaid expenses and other assets 219,615 255,055
Accounts payable (1,411,849) (943,416)
Accrued expenses 3,050,676 303,255
Net cash used in operating activities (13,702,233) (10,773,679)
Cash flows from investing activities:    
Purchases of property and equipment 0 (89,284)
Net cash used in investing activities 0 (89,284)
Cash flows from financing activities:    
Proceeds from exercise of stock options 721,195 50,960
Proceeds from exercise of warrants 0 3,745
Payments for debt issuance costs (90,000) 0
Net cash provided by (used in) financing activities 631,195 54,705
Net decrease in cash (13,071,038) (10,808,258)
Cash and cash equivalents at beginning of period 88,067,647 106,398,919
Cash and cash equivalents at end of period 74,996,609 95,590,661
Cash paid for:    
Interest $ 457,499 $ 343,125