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Accrued Expenses (Tables)
3 Months Ended
Mar. 31, 2018
Accrued Expenses [Abstract]  
Accrued Expenses and Other Liabilities
Accrued expenses and other liabilities consist of the following:

 
 
As of
March 31, 2018
  
As of
December 31, 2017
 
Accrued research and development costs (1)
 
$
7,729,749
  
$
2,857,025
 
Accrued professional fees
  
245,773
   
267,646
 
Accrued compensation
  
102,715
   
1,886,638
 
Accrued other
  
367,336
   
385,896
 
Deferred rent
  
27,308
   
25,000
 
Total
 
$
8,472,881
  
$
5,422,205
 

(1)
Balance as of March 31, 2018 includes estimated close down NEWTON 2 trial costs of $2.9 million and $2.0 million for CMO milestone payments.