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Statements of Cash Flows (Unaudited) - USD ($)
9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Cash flows from operating activities:    
Net loss $ (36,956,181) $ (29,305,801)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 4,637,142 4,029,326
Stock-based 401K company common match 170,620 0
Depreciation expense 134,569 60,331
Loss on disposal of fixed assets 0 102,789
Amortization of debt discount 28,871 60,206
Amortization of debt issuance costs 81,306 63,699
Non-cash interest expense 274,530 82,357
Changes in assets and liabilities:    
Prepaid expenses and other assets 627,848 633,513
Accounts payable (524,145) (399,708)
Accrued expenses 68,683 (1,469,109)
Net cash used in operating activities (31,456,757) (26,142,397)
Cash flows from investing activities:    
Purchases of property and equipment (160,751) (339,410)
Net cash used in investing activities (160,751) (339,410)
Cash flows from financing activities:    
Proceeds from issuance of debt 5,000,000 11,022,286
Proceeds from exercise of stock options 91,982 293,988
Proceeds from exercise of warrants 50,922 13,107
Payments for issuance costs 0 (544,773)
Payments for debt issuance costs 0 (219,042)
Repayment of debt 0 (1,488,558)
Proceeds from issuance of common stock, net of issuance costs 17,382,943 0
Net cash provided by (used in) financing activities 22,525,847 9,077,008
Net increase (decrease) in cash (9,091,661) (17,404,799)
Cash and cash equivalents at beginning of period 106,398,919 130,189,421
Cash and cash equivalents at end of period 97,307,258 112,784,622
Cash paid for:    
Interest 1,172,979 443,464
Supplemental cash flow information:    
Accrued capital expenditures included in accrued expenses and accounts payable $ 18,084 $ 348,591