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Summary of Significant Accounting Policies (Details) - shares
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Net Loss per Common Share [Abstract]      
Antidilutive securities excluded from computation of earnings per share (in shares) 5,857,926 4,902,451 11,835,766
Maximum [Member]      
Property and Equipment [Abstract]      
Estimated useful lives of property and equipment 5 years    
Minimum [Member]      
Property and Equipment [Abstract]      
Estimated useful lives of property and equipment 3 years    
Stock Options to Purchase Common Stock [Member]      
Net Loss per Common Share [Abstract]      
Antidilutive securities excluded from computation of earnings per share (in shares) 5,316,511 4,302,267 2,445,711
Convertible Preferred Stock to Purchase Common Stock [Member]      
Net Loss per Common Share [Abstract]      
Antidilutive securities excluded from computation of earnings per share (in shares) 0 0 8,695,092
Warrants to Purchase Common Stock [Member]      
Net Loss per Common Share [Abstract]      
Antidilutive securities excluded from computation of earnings per share (in shares) 541,415 600,184 99,401
Warrants to Purchase Series C Preferred Stock [Member]      
Net Loss per Common Share [Abstract]      
Antidilutive securities excluded from computation of earnings per share (in shares) 0 0 338,534
Warrants to Purchase Series C-1 Preferred Stock [Member]      
Net Loss per Common Share [Abstract]      
Antidilutive securities excluded from computation of earnings per share (in shares) 0 0 257,028