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Statements of Cash Flows (Unaudited) - USD ($)
9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Cash flows from operating activities:    
Net loss $ (29,305,801) $ (20,119,498)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 4,029,326 1,566,562
Warrant remeasurement 0 1,879,823
Depreciation expense 60,331 38,360
Loss on disposal of fixed assets 102,789 0
Amortization of debt discount 60,206 79,400
Amortization of debt issuance costs 63,699 0
Non-cash interest expense 82,357 28,667
Changes in assets and liabilities:    
Prepaid expenses and other assets 633,513 78,814
Accounts payable (399,708) (126,415)
Accrued expenses (1,469,109) 1,604,432
Net cash used in operating activities (26,142,397) (14,969,855)
Cash flows from investing activities:    
Purchases of property and equipment (339,410) (799,424)
Net cash used in investing activities (339,410) (799,424)
Cash flows from financing activities:    
Proceeds from issuance of debt 11,022,286 3,000,000
Proceeds from exercise of stock options 293,988 0
Proceeds from exercise of warrants 13,107 0
Payments for issuance costs (544,773) (474,357)
Payments for debt issuance costs (219,042) 0
Repayment of debt (1,488,558) 0
Proceeds from issuance of preferred stock, net of issuance costs 0 52,394,571
Net cash provided by financing activities 9,077,008 54,920,214
Net (decrease) increase in cash (17,404,799) 39,150,935
Cash and cash equivalents at beginning of period 130,189,421 13,728,972
Cash and cash equivalents at end of period 112,784,622 52,879,907
Cash paid for:    
Interest 443,464 412,717
Supplemental cash flow information:    
Deferred issuance costs included in accrued expenses and accounts payable 0 552,410
Non-cash financing costs 0 175,114
Accrued capital expenditures included in accrued expenses and accounts payable $ 348,591 $ 576,839