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Summary of Significant Accounting Policies (Details) - shares
9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Net Loss per Common Share [Abstract]    
Antidilutive securities excluded from computation of earnings per share (in shares) 5,711,216 22,495,252
Stock Options to Purchase Common Stock [Member]    
Net Loss per Common Share [Abstract]    
Antidilutive securities excluded from computation of earnings per share (in shares) 5,166,511 4,227,022
Convertible Preferred Stock to Purchase Common Stock [Member]    
Net Loss per Common Share [Abstract]    
Antidilutive securities excluded from computation of earnings per share (in shares) 0 17,497,815
Warrants to Purchase Common Stock [Member]    
Net Loss per Common Share [Abstract]    
Antidilutive securities excluded from computation of earnings per share (in shares) 544,705 99,401
Warrants to Purchase Series C Preferred Stock [Member]    
Net Loss per Common Share [Abstract]    
Antidilutive securities excluded from computation of earnings per share (in shares) 0 338,534
Warrants to Purchase Series C-1 Preferred Stock [Member]    
Net Loss per Common Share [Abstract]    
Antidilutive securities excluded from computation of earnings per share (in shares) 0 332,480