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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Cash flows from operating activities:    
Net loss $ (41,640) $ (129,492)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 611 157
Amortization of right-of-use asset 115 106
Accretion of discounts on marketable securities (818) (538)
Share-based compensation expense 5,703 2,159
Charge for purchase of in-process research and development assets   111,954
Changes in operating assets and liabilities:    
Prepaid expenses and other assets (1,707) 2,473
Accounts payable (3,810) 2,396
Accrued expenses and other current liabilities (8,521) 669
Deferred revenue (2,926) (1,029)
Operating lease liabilities (62) (25)
Net cash used in operating activities (53,055) (11,170)
Cash flows from investing activities:    
Purchases of in-process research and development assets (6,246) (35,067)
Maturities of marketable securities 15,000  
Purchases of property and equipment (3,665) (2,164)
Net cash provided by (used in) investing activities 5,089 (37,231)
Cash flows from financing activities:    
Proceeds from public offering 172,500 230,002
Payment of offering costs (10,485) (14,155)
Proceeds from exercise of stock options 213 171
Proceeds from exercise of common stock warrants   3,427
Net cash provided by financing activities 162,228 219,445
Net increase in cash and cash equivalents and restricted cash 114,262 171,044
Cash and cash equivalents and restricted cash at beginning of period 143,451 98,779
Cash and cash equivalents and restricted cash at end of period 257,713 269,823
Reconciliation of cash and cash equivalents and restricted cash:    
Cash and cash equivalents 257,613 269,723
Restricted cash 100 100
Total cash, cash equivalents, and restricted cash 257,713 269,823
Supplemental disclosures of non-cash investing and financing activities:    
Issuance of common stock in exchange for in-process research and development assets   74,033
Net liabilities assumed from purchases of in-process research and development assets   2,041
Purchase of in-process research and development assets in accounts payable and accrued expenses   813
Offering costs in accounts payable 270 437
Purchases of property and equipment in accounts payable and accrued expenses and other current liabilities $ 592 $ 594