Strategic transactions and agreements - Bristol-Myers Squibb (Details) - USD ($) $ / shares in Units, $ in Thousands		3 Months Ended
	Aug. 07, 2024	Mar. 31, 2025	Mar. 31, 2024	Mar. 25, 2024
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Issuance of common stock		$ 161,745	$ 215,410
Bristol myers squibb
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Maximum amount payable				$ 142,000
Commercial milestone payments				$ 50,000
Shares issued	230,415
Issuance of common stock	$ 2,700
Share price per share	$ 12.46
Percentage of discount related to unregistered share restrictions to be deducted from the share price	6.00%