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Consolidated Statements of Cash Flows - USD ($)
shares in Thousands, $ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Cash flows from operating activities:    
Net loss $ (292,963) $ (106,806)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 1,567 457
Amortization of right-of-use asset 535 271
Accretion of discounts on marketable securities (2,899) (512)
Share-based compensation expense 15,748 6,223
Charge for purchase of in-process research and development assets 152,344 80,802
Changes in operating assets and liabilities:    
Prepaid expenses and other assets 906 (4,144)
Accounts payable 9,526 (608)
Accrued expenses and other current liabilities 13,550 614
Deferred revenue (9,041) 15,982
Operating lease liabilities (67) 153
Net cash used in operating activities (110,794) (7,568)
Cash flows from investing activities:    
Purchases of in-process research and development assets (46,335)  
Purchases of marketable securities (186,555) (38,929)
Cash acquired in connection with Morphimmune merger, net of transaction costs   9,276
Maturities of marketable securities 155,000  
Purchases of property and equipment (7,173) (831)
Net cash used in investing activities (85,063) (30,484)
Cash flows from financing activities:    
Proceeds from public offering 230,002  
Payment of offering costs (15,228) (8,997)
Proceeds from PIPE transaction   125,000
Proceeds from exercise of stock options 2,024 371
Proceeds from exercise of common stock warrants 3,731  
Proceeds from issuance of common stock under ATM 20,000 34
Net cash provided by financing activities 240,529 116,408
Net increase in cash and cash equivalents and restricted cash 44,672 78,356
Cash and cash equivalents and restricted cash at beginning of period 98,779 20,423
Cash and cash equivalents and restricted cash at end of period 143,451 98,779
Reconciliation of cash and cash equivalents and restricted cash:    
Cash and cash equivalents 143,351 98,679
Restricted cash 100 100
Total cash, cash equivalents, and restricted cash 143,451 $ 98,779
Supplemental disclosures of non-cash investing and financing activities:    
Issuance of common stock and stock-based equity awards for the Morphimmune merger   87,161
Issuance of common stock in exchange for in-process research and development assets 97,722  
Net liabilities assumed from purchases of in-process research and development assets 2,041  
Purchase of in-process research and development assets in accounts payable and accrued expenses 6,246  
Right-of-use assets obtained in exchange for operating lease liabilities 1,189 $ 1,325
Remeasurement of operating right-of-use asset and lease liability due to lease modifications 2,035 226
Issuance of common stock to certain board of directors in lieu of accrued compensation   221
Purchases of property and equipment in accounts payable and accrued expenses and other current liabilities $ 2,806 $ 372