Strategic transactions and agreements - Other asset acquisitions and license agreements (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
In-process research and development	$ 152,344	$ 80,802
Other asset acquisitions and license agreements
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Accrued expenses and other current liabilities	800
Upfront consideration paid in cash	$ 10,800
In-process research and development		$ 0