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Summary of significant accounting policies - Property and Equipment (Details)
Dec. 31, 2024
Lab equipment  
Property, Plant and Equipment [Line Items]  
Property and equipment, estimated useful life 5 years
Computer equipment  
Property, Plant and Equipment [Line Items]  
Property and equipment, estimated useful life 3 years
Office equipment  
Property, Plant and Equipment [Line Items]  
Property and equipment, estimated useful life 5 years
Furniture and fixtures  
Property, Plant and Equipment [Line Items]  
Property and equipment, estimated useful life 5 years