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Share-based compensation - Option Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
9 Months Ended 12 Months Ended
Jun. 28, 2023
Sep. 30, 2024
Sep. 30, 2023
Dec. 31, 2023
Number of shares        
Options, Beginning balance   7,978,291    
Options, Granted   5,172,469    
Options, Exercised   (566,548)    
Options, Forfeited   (895,548)    
Options, Expired   (236,808)    
Options, Ending balance   11,451,856   7,978,291
Options, Exercisable   2,813,140    
Weighted Average Exercise price        
Beginning price   $ 6.15    
Granted   15.12    
Exercised   3.13    
Forfeited   8.18    
Expired   24.42    
Ending price   9.81   $ 6.15
Exercisable   $ 4.91    
Weighted average remaining contractual term        
Weighted Average Remaining Contractual Term   8 years 9 months   8 years 7 months 13 days
Weighted Average Remaining Contractual Term, Exercisable   6 years 10 months 20 days    
Weighted average grant date fair value   $ 11.47 $ 3.67  
Intrinsic value, outstanding   $ 65,609   $ 45,360
Intrinsic value, exercisable   29,667    
Intrinsic value, exercised   $ 8,100 $ 100  
Dr. Clay Siegall | Morphimmune Inc        
Number of shares        
Options, Granted 2,137,080      
Weighted Average Exercise price        
Granted $ 5.91