Licensing arrangements - Purdue research foundation and other license agreements (Details)	3 Months Ended	9 Months Ended
	Sep. 30, 2024 USD ($)	Sep. 30, 2024 USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
In-process research and development	$ 6,706,000	$ 124,972,000
License agreement with purdue research foundation
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Maximum amount payable	3,800,000	3,800,000
Other license agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Upfront consideration paid in cash	$ 4,000,000.0	4,600,000
In-process research and development		$ 0