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Share-based compensation - Plans (Details) - $ / shares
6 Months Ended
Jan. 01, 2024
Oct. 02, 2023
Jun. 30, 2024
Jun. 30, 2023
Oct. 02, 2024
Dec. 31, 2023
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Shares available for future issuance     14,554,376     13,202,327
Exercise price     $ 10.00      
Weighted average grant date fair value     $ 13.49 $ 3.67    
Morphimmune Inc            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Exercise price   $ 1.29        
Dr. Clay Siegall | Morphimmune Inc | One-year anniversary            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Percentage of vesting   25.00%        
Dr. Clay Siegall | Morphimmune Inc | Over next 36 months            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Vesting period   36 months        
Percentage of vesting   75.00%        
2020 Plan            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Shares available for grant     4,180,424      
Increase in shares available for future issuance 1,730,071          
MorphImmune Plan            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Shares available for grant         929,702  
Employee Stock Purchase Plan            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Shares available for grant     906,251     473,733
Increase in shares available for future issuance 432,518   906,251      
Stock issued during period     0