Nature of the business (Details) $ in Thousands	Mar. 31, 2024 USD ($) item	Dec. 31, 2023 USD ($)	Mar. 31, 2023 USD ($)
Nature of the business
Number of clinical assets | item	1
Number of preclinical assets | item	3
Accumulated deficit	$ (352,299)	$ (222,807)
Non-restricted cash and cash equivalents	269,723	98,679	$ 44,424
Marketable securities	$ 39,983	$ 39,463