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Share-based compensation - Costs (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock-based compensation expense $ 1,083 $ 1,340 $ 3,340 $ 3,977
Unrecognized compensation cost 7,400   $ 7,400  
Recognition period     1 year 2 months 12 days  
Research and development        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock-based compensation expense 466 480 $ 1,323 1,387
General and administrative        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock-based compensation expense $ 617 $ 860 $ 2,017 $ 2,590