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Summary of significant accounting policies - Anti-dilutive (Details) - shares
3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Earnings Per Share, Diluted, Other Disclosures [Abstract]    
Anti-dilutive securities 3,817,356 3,312,956
Stock options    
Earnings Per Share, Diluted, Other Disclosures [Abstract]    
Anti-dilutive securities 2,493,410 2,009,844
Common stock warrants    
Earnings Per Share, Diluted, Other Disclosures [Abstract]    
Anti-dilutive securities 1,303,112 1,303,112
Unvested restricted stock awards    
Earnings Per Share, Diluted, Other Disclosures [Abstract]    
Anti-dilutive securities 20,834