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Income taxes (Tables)
12 Months Ended
Dec. 31, 2022
Income taxes  
Schedule of reconciliation of the federal income tax rate

A reconciliation of the federal income tax rate to the Company’s effective tax rate is as follows:

    

Year ended

    

December 31, 

    

2022

    

2021

 

Federal tax benefit at statutory rate

21.0

%  

21.0

%

State tax, net of federal benefit

4.3

8.0

Effects of state tax legislation, net of federal benefit

(7.1)

Research and development credits

1.9

 

2.4

Permanent differences

(0.2)

 

0.3

Change in valuation allowance

(19.9)

 

(31.7)

%  

%

Schedule of Components of the Company's deferred taxes

    

Year ended

    

December 31, 

    

2022

    

2021

 

Federal tax benefit at statutory rate

21.0

%  

21.0

%

State tax, net of federal benefit

4.3

8.0

Effects of state tax legislation, net of federal benefit

(7.1)

Research and development credits

1.9

 

2.4

Permanent differences

(0.2)

 

0.3

Change in valuation allowance

(19.9)

 

(31.7)

%  

%