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Income taxes (Tables)
12 Months Ended
Dec. 31, 2022
Income taxes  
Schedule of reconciliation of the federal income tax rate

A reconciliation of the federal income tax rate to the Company’s effective tax rate is as follows:

​

​

​

​

​

​

​

​

    

Year ended

​

​

    

December 31, 

​

​

    

2022

    

2021

 

Federal tax benefit at statutory rate

​

21.0

%  

21.0

%

State tax, net of federal benefit

​

4.3

​

8.0

​

Effects of state tax legislation, net of federal benefit

​

(7.1)

​

—

​

Research and development credits

​

1.9

 

2.4

​

Permanent differences

​

(0.2)

 

0.3

​

Change in valuation allowance

​

(19.9)

 

(31.7)

​

​

​

—

%  

—

%

Schedule of Components of the Company's deferred taxes

​

​

​

​

​

​

​

​

    

Year ended

​

​

    

December 31, 

​

​

    

2022

    

2021

 

Federal tax benefit at statutory rate

​

21.0

%  

21.0

%

State tax, net of federal benefit

​

4.3

​

8.0

​

Effects of state tax legislation, net of federal benefit

​

(7.1)

​

—

​

Research and development credits

​

1.9

 

2.4

​

Permanent differences

​

(0.2)

 

0.3

​

Change in valuation allowance

​

(19.9)

 

(31.7)

​

​

​

—

%  

—

%