Document and Entity Information - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Mar. 13, 2023	Jun. 30, 2022
Document and Entity Information [Abstract]
Document Type	10-K
Document Annual Report	true
Document Period End Date	Dec. 31, 2022
Current Fiscal Year End Date	--12-31
Document Transition Report	false
Entity File Number	001-39580
Entity Registrant Name	IMMUNOME, INC.
Entity Incorporation, State or Country Code	DE
Entity Tax Identification Number	77-0694340
Entity Address, Address Line One	665 Stockton Drive
Entity Address, Address Line Two	Suite 300
Entity Address, City or Town	Exton
Entity Address State Or Province	PA
Entity Address, Postal Zip Code	19341
City Area Code	610
Local Phone Number	321-3700
Title of 12(b) Security	Common Stock, $0.0001 Par Value
Trading Symbol	IMNM
Security Exchange Name	NASDAQ
Entity Well-known Seasoned Issuer	No
Entity Voluntary Filers	No
Entity Current Reporting Status	Yes
Entity Interactive Data Current	Yes
Entity Filer Category	Non-accelerated Filer
Entity Small Business	true
Entity Emerging Growth Company	true
ICFR Auditor Attestation Flag	false
Entity Ex Transition Period	false
Entity Shell Company	false
Entity Public Float				$ 34.1
Entity Common Stock, Shares Outstanding			12,215,018
Auditor Name	Ernst & Young LLP	Deloitte & Touche LLP
Auditor Firm ID	42	34
Auditor Location	Philadelphia, Pennsylvania	Philadelphia, Pennsylvania
Entity Central Index Key	0001472012
Document Fiscal Year Focus	2022
Document Fiscal Period Focus	FY
Amendment Flag	false