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Nature of the business and basis of presentation (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2021
Oct. 01, 2021
Net loss $ (11,653) $ (3,898)    
Accumulated deficit (90,758)   $ (79,105)  
Cash and cash equivalents $ 42,879   $ 49,229  
Open Market Sale | Maximum        
Securities aggregate price       $ 75,000