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Summary of significant accounting policies - Anti-dilutive (Details) - shares
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Earnings Per Share, Diluted, Other Disclosures [Abstract]    
Anti-dilutive securities 3,308,868 2,508,036
Stock options    
Earnings Per Share, Diluted, Other Disclosures [Abstract]    
Anti-dilutive securities 2,005,756 1,472,840
Convertible preferred stock warrants    
Earnings Per Share, Diluted, Other Disclosures [Abstract]    
Anti-dilutive securities 1,303,112 1,035,196