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Share-based compensation - Costs (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
Aug. 31, 2020
Sep. 30, 2021
Sep. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Stock-based compensation expense $ 0 $ 1,155 $ 117 $ 2,229 $ 302
Unrecognized compensation cost   13,500   $ 13,500  
Recognition period       3 years 4 months 24 days  
Research and development          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Stock-based compensation expense   402 39 $ 924 94
General and administrative          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Stock-based compensation expense   $ 753 $ 78 $ 1,305 $ 208