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Share-based compensation - Costs (Details) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended
Aug. 31, 2020
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Stock-based compensation expense $ 0 $ 749,000 $ 39,000 $ 1,074,000 $ 185,000
Unrecognized compensation cost   12,900,000   $ 12,900,000  
Recognition period       3 years 7 months 6 days  
General and administrative          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Stock-based compensation expense   381,000 31,000 $ 552,000 130,000
Research and development          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Stock-based compensation expense   $ 368,000 $ 8,000 $ 522,000 $ 55,000