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Summary of significant accounting policies - Anti-dilutive (Details) - shares
3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Earnings Per Share, Diluted, Other Disclosures [Abstract]    
Anti-dilutive securities 2,659,599 5,464,615
Stock options    
Earnings Per Share, Diluted, Other Disclosures [Abstract]    
Anti-dilutive securities 1,636,069 1,016,634
Common stock warrants    
Earnings Per Share, Diluted, Other Disclosures [Abstract]    
Anti-dilutive securities 1,023,530  
Series A Preferred Convertible Stock    
Earnings Per Share, Diluted, Other Disclosures [Abstract]    
Anti-dilutive securities   4,447,981