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Share-based compensation - Plans (Details) - $ / shares
3 Months Ended
Jan. 01, 2026
Jun. 28, 2023
Mar. 31, 2026
Dec. 31, 2025
May 31, 2025
Oct. 31, 2024
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Shares available for future issuance     25,349,079 19,861,949    
Options, Granted     500,000      
Granted     $ 22.53      
Dr. Clay Siegall | Morphimmune Inc            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Options, Granted   2,137,080        
2020 Plan            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Increase in shares available for future issuance 4,525,327   5,094,182      
2024 Inducement Plan            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Shares available for future issuance           2,000,000
Shares available for grant     927,551      
2024 Inducement Plan | Minimum            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Shares available for future issuance         2,000,000  
2024 Inducement Plan | Maximum            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Shares available for future issuance         3,500,000  
MorphImmune Plan            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Shares available for future issuance     558,377      
Employee Stock Purchase Plan            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Increase in shares available for future issuance 1,000,000          
Shares available for grant     2,550,859 1,550,859    
Awards granted     0