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Share-based compensation - Plans (Details) - $ / shares				1 Months Ended		12 Months Ended
Share-based compensation - Plans (Details) - $ / shares	Jan. 01, 2026	Jan. 01, 2025	Jun. 28, 2023	Sep. 30, 2020	Aug. 31, 2020	Dec. 31, 2025	May 31, 2025	Dec. 31, 2024	Oct. 31, 2024
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Shares available for future issuance						19,861,949		15,528,401
Options, Granted						5,562,784
Granted						$ 10.36
Dr. Clay Siegall \| Morphimmune Inc
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Options, Granted			2,137,080
2020 Plan
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Threshold Percentage Of Total Number Of Common Stock Outstanding					4.00%
Shares available for future issuance						644,655
Expiration period						10 years
2020 Plan \| Subsequent events
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Increase in shares available for future issuance	4,525,327
2020 Plan \| Maximum
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Vesting period						4 years
2020 Plan \| Minimum
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Vesting period						1 year
2024 Inducement Plan
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Shares available for future issuance									2,000,000
Shares available for grant						1,251,300
2024 Inducement Plan \| Maximum
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Shares available for future issuance							3,500,000
2024 Inducement Plan \| Minimum
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Shares available for future issuance							2,000,000
MorphImmune Plan
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Shares available for future issuance						558,377
Employee Stock Purchase Plan
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Increase in shares available for future issuance		1,000,000
Authorized stock options						125,000
Employee Stock Purchase Plan, Threshold Period For Which Common Stock Is Automatically Added To Arrive At Authorized Shares						10 years
Percentage of outstanding capital stock						1.00%
Purchase price percentage				85.00%
Maximum number of shares that can be purchased				15.00%
Number of common shares added in authorized						1,000,000
Shares available for grant						1,550,859		906,251
Awards granted						0