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Strategic transactions and agreements - Bristol-Myers Squibb - Varegacestat (Details) - Bristol myers squibb - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Aug. 07, 2024
Dec. 31, 2024
Mar. 25, 2024
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Maximum amount payable     $ 142,000
Commercial milestone payments     $ 50,000
Shares issued 230,415    
Issuance of common stock $ 2,700 $ 2,699  
Share price per share $ 12.46    
Percentage of discount related to unregistered share restrictions to be deducted from the share price 6.00%