Condensed Consolidated Statements of Changes in Stockholders Equity - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Other Comprehensive Income	Accumulated Deficit	Zentalis Asset Purchase Agreement	Zentalis Asset Purchase Agreement Common Stock	Zentalis Asset Purchase Agreement Additional Paid-in Capital	Ayala Asset Purchase Agreement	Ayala Asset Purchase Agreement Common Stock	Ayala Asset Purchase Agreement Additional Paid-in Capital	ATM	ATM Common Stock	ATM Additional Paid-in Capital	Public offering	Public offering Common Stock	Public offering Additional Paid-in Capital	BMS License Agreement	BMS License Agreement Common Stock	BMS License Agreement Additional Paid-in Capital
Balance at Dec. 31, 2023	$ 119,882	$ 4	$ 342,663	$ 22	$ (222,807)
Balance (in shares) at Dec. 31, 2023		43,251,778
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Share-based compensation expense	2,159		2,159
Issuance of common stock						$ 23,388		$ 23,388	$ 50,645		$ 50,645				$ 215,410	$ 2	$ 215,408
Issuance of common stock (in shares)							2,298,586			2,175,489						11,500,000
Exercise of stock options	171		171
Exercise of stock options (in shares)		125,704
Exercise of common stock warrants	3,427		3,427
Exercise of common stock warrants (in shares)		342,686
Unrealized gain (loss) on marketable securities	(18)			(18)
Net loss	(129,492)				(129,492)
Balance at Mar. 31, 2024	285,572	$ 6	637,861	4	(352,299)
Balance (in shares) at Mar. 31, 2024		59,694,243
Balance at Dec. 31, 2023	119,882	$ 4	342,663	22	(222,807)
Balance (in shares) at Dec. 31, 2023		43,251,778
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(212,714)
Balance at Sep. 30, 2024	214,906	$ 6	650,351	70	(435,521)
Balance (in shares) at Sep. 30, 2024		60,422,062
Balance at Mar. 31, 2024	285,572	$ 6	637,861	4	(352,299)
Balance (in shares) at Mar. 31, 2024		59,694,243
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Share-based compensation expense	3,227		3,227
Exercise of stock options	859		859
Exercise of stock options (in shares)		289,041
Exercise of common stock warrants	304		304
Exercise of common stock warrants (in shares)		30,371
Unrealized gain (loss) on marketable securities	(2)			(2)
Net loss	(36,122)				(36,122)
Balance at Jun. 30, 2024	253,838	$ 6	642,251	2	(388,421)
Balance (in shares) at Jun. 30, 2024		60,013,655
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Share-based compensation expense	4,892		4,892
Issuance of common stock																		$ 2,699		$ 2,699
Issuance of common stock (in shares)																			230,415
Exercise of stock options	509		509
Exercise of stock options (in shares)		177,992
Unrealized gain (loss) on marketable securities	68			68
Net loss	(47,100)				(47,100)
Balance at Sep. 30, 2024	214,906	$ 6	650,351	70	(435,521)
Balance (in shares) at Sep. 30, 2024		60,422,062
Balance at Dec. 31, 2024	181,165	$ 6	696,872	57	(515,770)
Balance (in shares) at Dec. 31, 2024		64,460,829
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Share-based compensation expense	5,703		5,703
Issuance of common stock															$ 161,745	$ 3	$ 161,742
Issuance of common stock (in shares)																22,258,064
Exercise of stock options	213		213
Exercise of stock options (in shares)		236,962
Unrealized gain (loss) on marketable securities	(60)			(60)
Net loss	(41,640)				(41,640)
Balance at Mar. 31, 2025	307,126	$ 9	864,530	(3)	(557,410)
Balance (in shares) at Mar. 31, 2025		86,955,855
Balance at Dec. 31, 2024	$ 181,165	$ 6	696,872	57	(515,770)
Balance (in shares) at Dec. 31, 2024		64,460,829
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock (in shares)												4,625,156
Exercise of stock options (in shares)	381,992
Net loss	$ (142,494)
Balance at Sep. 30, 2025	263,919	$ 9	922,174		(658,264)
Balance (in shares) at Sep. 30, 2025		91,706,948
Balance at Mar. 31, 2025	307,126	$ 9	864,530	(3)	(557,410)
Balance (in shares) at Mar. 31, 2025		86,955,855
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Share-based compensation expense	5,347		5,347
Exercise of stock options	215		215
Exercise of stock options (in shares)		56,980
Unrealized gain (loss) on marketable securities	(21)			(21)
Net loss	(43,397)				(43,397)
Balance at Jun. 30, 2025	269,270	$ 9	870,092	(24)	(600,807)
Balance (in shares) at Jun. 30, 2025		87,012,835
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Share-based compensation expense	6,747		6,747
Issuance of common stock												$ 44,924		$ 44,924
Issuance of common stock (in shares)												4,625,156	4,625,156
Exercise of stock options	411		411
Exercise of stock options (in shares)		68,957
Unrealized gain (loss) on marketable securities	24			$ 24
Net loss	(57,457)				(57,457)
Balance at Sep. 30, 2025	$ 263,919	$ 9	$ 922,174		$ (658,264)
Balance (in shares) at Sep. 30, 2025		91,706,948