Leases - Additional lease related information (Details) - Office and laboratory space	Sep. 30, 2025	Dec. 31, 2024
Lessee, Lease, Description [Line Items]
Weighted-average remaining lease term (in years)	7 years 6 months	8 years 1 month 24 days
Weighted-average discount rate	8.70%	9.50%

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 842
-SubTopic 20
-Name Accounting Standards Codification
-Section 50
-Paragraph 7A
-Subparagraph (c)
-Publisher FASB
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Reference 2: http://www.xbrl.org/2003/role/disclosureRef
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- Definition

Weighted average discount rate for operating lease calculated at point in time.

+ References

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-Topic 842
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-Name Accounting Standards Codification
-Section 55
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Reference 2: http://www.xbrl.org/2003/role/disclosureRef
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- Definition

Weighted average remaining lease term for operating lease, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

+ References

Reference 1: http://www.xbrl.org/2003/role/exampleRef
-Topic 842
-SubTopic 20
-Name Accounting Standards Codification
-Section 55
-Paragraph 53
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479589/842-20-55-53

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
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-Publisher FASB
-URI https://asc.fasb.org/1943274/2147478964/842-20-50-4

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